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 Subject :The Knock Out Rat Consortium (KORC).. 2010-08-21 22:26:24 
Harrison
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Joined: 2009-07-13 23:53:04
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Dear friends,

The Knock Out Rat Consortium (KORC) is formed by individuals and institutions interested in the goal of creating knockout rats using multiple different technologies. Knockout rats can be used for functional genomics and also for drug discovery.  The mission of the KORC is to create rats with single gene disruptions (knockouts) using all available technology.  KORC goal is create at least one rat with a null mutation corresponding to every gene in the rat genome.  KORC will create all mutations on the same background strain of rat, namely Fischer.  Each knockout will be bred into at least one male rat, which will be sacrificed for tissue collection and cryopreservation of sperm.  Cryopreserved sperm can be used to create knockout rats with specific null mutations by the process called intracytoplasmic sperm injection (ICSI).

Visit at http://www.knockoutrat.org/

Kind regards,
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