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Prototype devices

It is recognized that a manufacturer may wish to submit a small number  of "prototype models" of a device to clinical investigation in order to assess safety and/or performance; and those such prototypes may need to undergo a number of changes prior to large-scale production.
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Investigational immunotherapy was safe, tolerable, and showed some activity against melanoma
Source:  Clinical Trials/Drug Trials News from Medical News Today
The investigational immunotherapeutic IMC-20D7S was safe, well tolerated, and showed signs of modest clinical activity for patients with advanced melanoma, according to results from a...
Positive pivotal Phase 3 data announced demonstrating investigational Elagolix reduced endometriosis-associated pain
Source:  Clinical Trials/Drug Trials News from Medical News Today
AbbVie, a global biopharmaceutical company in cooperation with Neurocrine Biosciences, Inc.
Depression could be treated with anti-inflammatory drugs
Source:  Clinical Trials/Drug Trials News from Medical News Today
A new meta-analysis finds a new class of drugs used to treat inflammation in autoimmune diseases may also be an effective treatment for depression.
The placebo effect: Knowingly taking sham pills may reduce chronic pain
Source:  Clinical Trials/Drug Trials News from Medical News Today
New study suggests it is not the expectation that a 'dummy pill' is real that elicits the placebo effect, but rather the ritual associated with taking it.
Caffeine did not induce arrhythmia in trial with heart failure patients
Source:  Clinical Trials/Drug Trials News from Medical News Today
A trial where heart failure patients ingested 500 mg caffeine over 5 hours found no raised risk of arrhythmic episodes, even during treadmill stress test.
Breast cancer drug shows potential in patients with skin metastases
Source:  Clinical Trials/Drug Trials News from Medical News Today
A study presented at the ESMO Congress reveals how the drug tucatinib led to a reduction in skin metastases for patients with breast cancer.
Cabozantinib improves progression-free survival in metastatic renal cell carcinoma
Source:  Clinical Trials/Drug Trials News from Medical News Today
Cabozantinib significantly improves progression-free survival and response rate in patients with metastatic renal cell carcinoma compared to sunitinib, according to research presented at the ESMO...
MEK inhibition in KRAS-mutant non-small-cell lung cancer (NSCLC) did not improve survival
Source:  Clinical Trials/Drug Trials News from Medical News Today
MEK inhibitor selumetinib in combination with docetaxel does not improve progression free or overall survival in individuals with KRAS-mutant non-small-cell lung cancer (NSCLC), according to data...
Custirsen shows no survival benefits in metastatic prostate cancer
Source:  Clinical Trials/Drug Trials News from Medical News Today
A phase III randomized controlled trial of custirsen in combination with cabazitaxel/prednisone in patients with previously-treated metastatic, castration-resistant prostate cancer has shown no...
Greater patient selection may be needed for first line nivolumab to improve progression-free survival in advanced lung cancer
Source:  Clinical Trials/Drug Trials News from Medical News Today
Greater patient selection may be needed for first line nivolumab to improve progression-free survival over chemotherapy in advanced lung cancer as the CheckMate 026 trial gave negative results in a...